Are you passionate about using computational approaches to solve complex biological challenges? Join the Tanaka Group at Imperial College London as a PhD student and play a pivotal role in advancing our understanding of skin pH regulation through computational modelling.
This exciting PhD project, supported by Procter & Gamble and funded by the EPSRC Industry Doctoral Landscape Awards (IDLA), offers a unique opportunity to work at the intersection of academic research and industry innovation.
The project is expected to start in October 2025. The funding will cover stipend and home fees for 4 years. There is a possibility to accept international students.
Project Overview
Skin barrier homeostasis emerges from a delicate interplay between cellular processes such as proliferation, differentiation, enzymatic activity, and the influence of the skin microbiome—all of which are regulated by pH. In this project, you will develop a biology-based computational model to uncover the mechanisms of pH regulation in human epidermal tissue.
Your work will focus on:
Exploring the dynamics of skin barrier homeostasis.
Simulating the epidermis’ responses to consumer-relevant perturbations, such as occlusion or microbial colonization.
Identifying novel strategies to promote and maintain healthy skin under challenging conditions.
This project will provide you with the opportunity to delve into the rich complexity of human biology while applying cutting-edge computational approaches. The insights gained will have real-world implications, shaping innovative interventions for skin health and beyond.
Who Should Apply?
We’re looking for motivated and talented individuals with:
Strong mathematical and programming skills and experience in mechanistic modelling of biological systems.
A Master’s degree in computational systems biology, applied mathematics, or a closely related field.
A basic understanding of biology.
Excellent interpersonal, written, and oral communication skills.
A collaborative spirit, alongside the ability to work independently and contribute to a team.
Why Join Us?
At the Tanaka Group, you’ll find a supportive, inclusive, and stimulating research environment where your growth and success are our priorities. By joining our team, you’ll benefit from:
Working on a cutting-edge, interdisciplinary project with direct industry relevance.
A friendly and diverse team that values open scientific discussions and creative thinking.
A chance to make a tangible impact on society by addressing real-world challenges in skin health.
Opportunities for collaboration with world-leading researchers at Imperial College London.
If you’re ready to embark on a journey of discovery and innovation, we’d love to hear from you. Apply today and become part of a team dedicated to pushing the boundaries of computational biology and making a difference in people’s lives.
How to Apply
Please email Professor Reiko Tanaka (r.tanaka@imperial.ac.uk) your CV and personal statement. The application will be considered on a rolling basis.
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